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apalutamide will lower the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with medicine which have been CYP2C19 substrates may end up in reduced publicity to these prescription drugs.Commonly, non-benzodiazepines have fewer d